Spray Congealing

Tailored Particle Formation Solutions for Stability and Controlled Release in Pharmaceuticals

Industrial spray congealing system featuring interconnected stainless steel components, including a conical vessel and piping, used for particle formation in pharmaceutical manufacturing.

One of the most pressing challenges in the pharmaceutical market is the reliable encapsulation and stabilization of temperature-sensitive and volatile compounds. This challenge is effectively addressed by spray congealing, a technology that forms solid particles through the low-temperature solidification of molten solutions.


Schedio Group’s spray congealing process is suited for encapsulating sensitive ingredients, ensuring stability for compounds that may degrade under higher temperatures. This method is utilized to create uniform microspheres for controlled-release formulations and to protect volatile ingredients.


We strive to be a reliable partner, offering tailored solutions that meet safety standards, timeline expectations, and budget needs. Our focus is on building long-term collaborations, supported by ongoing technical expertise, process guidance, and after-sales support.


The spray congealing process offers flexibility in particle size customization, supporting specific formulation requirements and enabling scalability from laboratory research to full production, all while maintaining consistent quality and control.

Spray Congealing Overview

The spray congealing technique involves the atomization of a mixture of molten substances in an environment with a temperature lower than the solidifying temperature of that same material. The sudden temperature drop determines the solidification of the atomized material and the formation of nearly spherical solid micro or nano-particles.


There are multiple applications of the spray chilling technology: as an example, the encapsulation of milk enzymes, vitamins or aromas within the food sector. In the pharmaceutical field, the use of lipidic matrix systems, which can also be produced using this technique, allow to determine predictable and stable release performances of active ingredients, is becoming increasingly frequent.


Features of Our Spray Congealing Technology


  • Full Process Control: Operable via a large LCD touch screen. Customizable
  • Design: Options for different cooling mediums and nozzle configurations.
  • Mobility and Convenience: Designed with wheels for easy movement and a compact structure fitting well in small spaces.
  • Advanced Data Capabilities: Supports multiple data recordings with connectivity options like USB, LAN, and Wi-Fi.
  • Regulatory Compliance: Suitable for clinical productions with options for compliance with industry standards.


Benefits


  • Efficiency: High throughput with precise control over particle size and distribution.
  • Flexibility: Spray congealing and spray drying in one equipment. From Spray Drying to Congealing in one touch.
  • Scalability: Suitable for R&D, pilot, and full-scale production.


Technical Info


  • Throughput Capacity: Customizable depending on specific needs, ranging from small-scale to large-scale production.
  • Cooling Medium: Various options including air, nitrogen, or custom solutions based on material requirements.
  • Configuration: Open loop or closed loop available

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Technical Info

Spray Congealing
SPRAY CONGEALING APT 2 SPRAY CONGEALING APT 5 SPRAY CONGEALING APT 5+ SPRAY CONGEALING APT30
Spray Congealing Capacity (Kg/h) 2.5 Kg/h 9 Kg/h 16 Kg/h 50 Kg/h
Technical line drawing of an industrial processing system with interconnected pipes, valves, and chambers, used for particle separation and filtration in pharmaceutical manufacturing.

Direct Line

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